Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.40 |
| ▸ | ATG7 | O95352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 4/20 | 0.38 |
| ▸ | HCK | P08631 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372346 | 0.81 | ALDH1A1 (0.48) | DYRK1AADORA2AADORA1PI4KBPI4KA | |
| SCHEMBL21362197 | 0.79 | ATG7 (0.39) | DYRK1ALRRK2ADORA2AADORA1PI4KB | |
| SCHEMBL21372047 | 0.78 | PI4KA (0.41) | DYRK1API4KBPI4KAPI4K2BPI4K2A | |
| SCHEMBL24504225 | 0.76 | YTHDC1 (0.44) | ADORA2AADORA1EGFRPIK3CDSRC | |
| SCHEMBL21372141 | 0.70 | PI4KA (0.35) | DYRK1AADORA2AADORA1PI4KBPI4KA | |
| SCHEMBL10371037 | 0.68 | LRRK2 (0.49) | DYRK1ALRRK2ADORA2AADORA1PIK3CD | |
| SCHEMBL12391467 | 0.67 | ADORA2A (0.43) | DYRK1ALRRK2ADORA2AADORA1PI4KB | |
| SCHEMBL4707558 | 0.66 | KDM4E (0.39) | — | |
| SCHEMBL30057955 | 0.66 | KDM4E (0.39) | — | |
| SCHEMBL24500019 | 0.65 | KDM5B (0.32) | ADORA2AADORA1PI4KBPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |