Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362375 | 0.87 | TSHR (0.40) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL21362290 | 0.85 | PTGS2 (0.35) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL21362369 | 0.83 | TSHR (0.39) | NPC1MAPTPTGS2USP2POLB | |
| SCHEMBL21362289 | 0.81 | PTGS2 (0.34) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL21362292 | 0.79 | NPC1 (0.50) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL21362291 | 0.77 | NPC1 (0.45) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL21352473 | 0.76 | MAPT (0.75) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL30843249 | 0.76 | MAPT (0.75) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL21362371 | 0.74 | NPC1 (0.48) | NPC1MAPTPTGS2LMNAUSP2 | |
| SCHEMBL15178580 | 0.72 | ALOX5 (0.41) | NPC1MAPTLMNARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190288223-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190288223-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | TPO, RPLP0, RPS10 | NPC1 4210/4885MAPT 463/4885PTGS2 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.