Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HRAS | P01112 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853411 | 0.75 | TAAR1 (0.48) | NPC1RAB9AALDH1A1HRAS | |
| SCHEMBL7140937 | 0.74 | NPC1 (0.49) | NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL13244660 | 0.71 | ABCB1 (0.51) | FOLH1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL30278712 | 0.71 | ABCB1 (0.51) | FOLH1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL27368867 | 0.70 | SLC1A1 (0.50) | FOLH1CTSK | |
| SCHEMBL16898610 | 0.70 | HRAS (0.42) | NPC1RAB9AALDH1A1HRASHPGD | |
| SCHEMBL1240611 | 0.69 | HRAS (0.46) | NPC1RAB9AALDH1A1HRAS | |
| SCHEMBL9157683 | 0.69 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1HRASMAOB | |
| SCHEMBL20363032 | 0.69 | ALDH1A1 (0.50) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL9543244 | 0.69 | HTT (0.53) | FOLH1NPC1RAB9AALDH1A1HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |