Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26971076 | 0.91 | POLB (0.33) | POLBL3MBTL1S1PR1ALOX15ALOX12 | |
| SCHEMBL25907540 | 0.82 | CD44 (0.41) | ALOX15ALOX12 | |
| SCHEMBL24698734 | 0.81 | ALDH1A1 (0.36) | POLBL3MBTL1ALOX15ALOX12 | |
| SCHEMBL22504864 | 0.81 | SHBG (0.34) | ALOX15ALOX12 | |
| SCHEMBL20141110 | 0.79 | POLB (0.35) | POLBL3MBTL1ALOX15ALOX12 | |
| SCHEMBL6827994 | 0.79 | ALOX15 (0.34) | POLBL3MBTL1ALOX15ALOX12 | |
| SCHEMBL16860939 | 0.79 | AHR (0.31) | ALOX15ALOX12 | |
| SCHEMBL670879 | 0.79 | AHR (0.41) | ALOX15ALOX12 | |
| SCHEMBL17466153 | 0.77 | CD44 (0.41) | L3MBTL1ALOX15ALOX12 | |
| SCHEMBL21404025 | 0.76 | AHR (0.40) | POLBL3MBTL1S1PR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |