SCHEMBL21362548

SCHEMBL21362548

[CH2]CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2988834 1.00 LMNA (0.38) LMNATHRB
SCHEMBL5484331 1.00 LMNA (0.38) LMNATHRB
SCHEMBL28758061 1.00 LMNA (0.38) LMNATHRB
SCHEMBL503245 1.00 LMNA (0.38) LMNATHRB
SCHEMBL206564 1.00 LMNA (0.38) LMNATHRB
SCHEMBL713096 1.00 LMNA (0.38) LMNATHRB
SCHEMBL200568 1.00 LMNA (0.38) LMNATHRB
SCHEMBL503931 1.00 LMNA (0.38) LMNATHRB
SCHEMBL200963 1.00 LMNA (0.38) LMNATHRB
SCHEMBL5485826 1.00 LMNA (0.38) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421872-B1 Stain resistant coating composition THE SHERWIN-WILLIAMS COMPANY (US) 2019-09-24 US disclosed