SCHEMBL503245

SCHEMBL503245

[CH2]CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2988834 1.00 LMNA (0.38) LMNATHRB
SCHEMBL5484331 1.00 LMNA (0.38) LMNATHRB
SCHEMBL28758061 1.00 LMNA (0.38) LMNATHRB
SCHEMBL206564 1.00 LMNA (0.38) LMNATHRB
SCHEMBL713096 1.00 LMNA (0.38) LMNATHRB
SCHEMBL200568 1.00 LMNA (0.38) LMNATHRB
SCHEMBL503931 1.00 LMNA (0.38) LMNATHRB
SCHEMBL200963 1.00 LMNA (0.38) LMNATHRB
SCHEMBL21362548 1.00 LMNA (0.38) LMNATHRB
SCHEMBL5485826 1.00 LMNA (0.38) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107429145-B Release agent composition for silicone pressure-sensitive adhesive, release film, and laminate 信越化学工业株式会社 2021-06-08 CN claimed
US-20200131410-A1 RELEASE AGENT COMPOSITION FOR SILICONE PRESSURE-SENSITIVE ADHESIVE AND RELEASE FILM DOW TORAY CO LTD (JP) 2020-04-30 US claimed
EP-3643760-A1 RELEASANT COMPOSITION FOR PRESSURE-SENSITIVE SILICONE ADHESIVE AND RELEASE FILM Dow Toray Co., Ltd. (JP) 2020-04-29 EP claimed
US-10563063-B2 Release agent composition for silicone adhesive, release film, and laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-18 US claimed
CN-110691825-A Release agent composition for silicone adhesive and release film 陶氏东丽株式会社 2020-01-14 CN claimed
EP-3275961-B1 LAMINATE COMPRISING RELEASE LINER BASED ON RELEASE AGENT COMPOSITION FOR SILICONE ADHESIVE SHINETSU CHEMICAL CO (JP) 2019-10-30 EP claimed
EP-3536757-A1 RELEASE AGENT COMPOSITION FOR SILICONE ADHESIVE AND RELEASE LINER Shin-Etsu Chemical Co., Ltd. (JP) 2019-09-11 EP claimed
US-20180086915-A1 RELEASE AGENT COMPOSITION FOR SILICONE ADHESIVE, RELEASE FILM, AND LAMINATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US claimed
EP-3275961-A1 RELEASE AGENT COMPOSITION FOR SILICONE ADHESIVE, RELEASE FILM, AND LAMINATE Shin-Etsu Chemical Co., Ltd. (JP) 2018-01-31 EP claimed
US-12037525-B2 Curable silicone composition, release coating agent comprising said composition, release film obtained using said release coating agent, and layered product including said release film DOW TORAY CO., LTD. (JP) 2024-07-16 US disclosed
US-12011904-B2 Production method for laminate of fluorosilicone rubber and silicone rubber DOW TORAY CO., LTD. (JP) 2024-06-18 US disclosed
CN-111129578-B Hybrid electrolyte, electrode and lithium battery each including the same, and method of manufacturing the same 三星电子株式会社 2024-06-04 CN disclosed
US-20240174815-A1 ORGANOPOLYSILOXANE COMPOSITION DOW TORAY CO LTD (JP) 2024-05-30 US disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
EP-0113127-B1 PROCESS FOR PREPARING DIORGANOPOLYSILOXANE CONTAINING FLUOROALKYL GROUPS Wacker-Chemie GmbH (DE) 1990-03-07 EP disclosed
US-4577040-A Method for preparing diorganopolysiloxanes containing fluoroalkyl groups WACKER-CHEMIE GMBH (DE) 1986-03-18 US disclosed
EP-0113127-A2 Process for preparing diorganopolysiloxane containing fluoroalkyl groups Wacker-Chemie GmbH (DE) 1984-07-11 EP disclosed
US-4360631-A MOISTURE-CURABLE MIXTURE OF ENCAPPED POLYDIORGANOSILOXANE, METHYLVINYLDI/EPSILON-CAPROLACTAMO/SILANE, AND AN HYDROXYLAMINE-MODIFIED POLYSILOXANE; SEALANTS; JOINTS; PAVING DOW CORNING CORPORATION (US) 1982-11-23 US disclosed
US-3996184-A CONSTRUCTION MATERIALS DOW CORNING CORPORATION (US) 1976-12-07 US disclosed
US-3989666-A ACETYLENIC ALCOHOLS, SILOXANES DOW CORNING CORPORATION (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 LMNA 4131/4885THRB 1472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.