Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L11 | O43521 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550064 | 0.82 | SMN1; SMN2 (0.46) | POLBHPGD | |
| SCHEMBL21352170 | 0.80 | HPGD (0.43) | HPGD | |
| SCHEMBL21564732 | 0.79 | RECQL (0.45) | POLB | |
| SCHEMBL21550071 | 0.77 | MKNK1 (0.37) | POLB | |
| SCHEMBL21362762 | 0.74 | PTPN1 (0.33) | BCL2L11BCL2L1MCL1PTGS2HPGD | |
| SCHEMBL21550037 | 0.74 | TSHR (0.44) | — | |
| SCHEMBL20157796 | 0.72 | SRD5A2 (0.43) | POLB | |
| SCHEMBL20157336 | 0.71 | NPC1 (0.40) | HPGD | |
| SCHEMBL21550104 | 0.71 | HPGD (0.35) | HPGD | |
| SCHEMBL20158041 | 0.70 | RAB9A (0.39) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |