Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352170 | 0.86 | HPGD (0.43) | HPGDALDH1A1LMNAGAAPKM | |
| SCHEMBL21550092 | 0.80 | HPGD (0.34) | HPGDALDH1A1P2RX7 | |
| SCHEMBL21550084 | 0.79 | RAB9A (0.37) | HPGDALDH1A1LMNA | |
| SCHEMBL20157556 | 0.78 | LMNA (0.44) | HPGDALDH1A1LMNA | |
| SCHEMBL21550433 | 0.77 | CYP4F2 (0.40) | HPGDRORC | |
| SCHEMBL20157336 | 0.77 | NPC1 (0.40) | HPGDALDH1A1LMNAGAA | |
| SCHEMBL20157803 | 0.77 | CES2 (0.47) | — | |
| SCHEMBL21550064 | 0.77 | SMN1; SMN2 (0.46) | HPGDALDH1A1 | |
| SCHEMBL21564732 | 0.77 | RECQL (0.45) | RORCALDH1A1LMNA | |
| SCHEMBL20157796 | 0.75 | SRD5A2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214399-A1 | BENZO- SEVEN-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | 罗欣药业(上海)有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |