Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 2/20 | 0.31 |
| ▸ | FLT4 | P35916 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158005 | 0.83 | HPGD (0.39) | PTPN1FLT1FLT4KDRHPGD | |
| SCHEMBL21362178 | 0.82 | NPC1 (0.41) | PTPN1FLT1FLT4KDRHPGD | |
| SCHEMBL21362707 | 0.74 | BCL2L11 (0.32) | MCL1HPGDBCL2L11BCL2L1PTGS2 | |
| SCHEMBL21362746 | 0.74 | TAS1R3 (0.35) | MCL1HPGDPTGS2 | |
| SCHEMBL21550050 | 0.73 | SMN1; SMN2 (0.42) | FLT1FLT4KDRALDH1A1 | |
| SCHEMBL20157822 | 0.72 | HPGD (0.38) | FLT1FLT4KDRHPGDALDH1A1 | |
| SCHEMBL21564804 | 0.72 | CA1 (0.39) | HPGD | |
| SCHEMBL20157769 | 0.71 | HPGD (0.39) | FLT1FLT4KDRHPGDALDH1A1 | |
| SCHEMBL20157951 | 0.71 | MAPT (0.47) | PTPN1ALDH1A1 | |
| SCHEMBL21564734 | 0.71 | RECQL (0.40) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |