SCHEMBL21362723

SCHEMBL21362723

O=C(N[C@H]1CCOC1)OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
GAA P10253 1/20 0.64
TSHR P16473 1/20 0.61
EPHX1 P07099 1/20 0.58
CTSL P07711 1/20 0.55
CTSB P07858 1/20 0.55
CTSK P43235 1/20 0.55
TLR4 O00206 1/20 0.51
DPP4 P27487 3/20 0.50
DPP7 Q9UHL4 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
KCNH2 Q12809 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ACHE P22303 1/20 0.50
CPB1 P15086 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472602 1.00 ALDH1A1 (0.64) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL22905145 1.00 ALDH1A1 (0.64) ALDH1A1GAATSHREPHX1CTSL
Hydrochloric Acid SCHEMBL27603388 0.99 ALDH1A1 (0.63) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL6888432 0.93 ALDH1A1 (0.70) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL31380843 0.92 EPHX1 (0.62) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL12526046 0.92 EPHX1 (0.62) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL6887982 0.92 EPHX1 (0.62) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL1192342 0.91 ALDH1A1 (0.64) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL1192341 0.91 ALDH1A1 (0.64) ALDH1A1GAATSHREPHX1CTSL
Hydrochloric Acid SCHEMBL31380782 0.91 EPHX1 (0.61) ALDH1A1GAATSHREPHX1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020046403-A1 NOVEL PROCESS FOR THE PREPARATION OF ENANTIOPURE 3- ENANTIOPURE 3-AMINO TETRAHYDROFURAN AND ITS SALTS MAJEED MUHAMMED (US) 2020-03-05 WO disclosed
WO-2020046403-A1 NOVEL PROCESS FOR THE PREPARATION OF ENANTIOPURE 3- ENANTIOPURE 3-AMINO TETRAHYDROFURAN AND ITS SALTS MAJEED MUHAMMED (US) 2020-03-05 WO disclosed
US-10421734-B1 Process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts SAMI LABS LIMITED (IN) 2019-09-24 US disclosed
US-10421734-B1 Process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts SAMI LABS LIMITED (IN) 2019-09-24 US disclosed
CN-1106001-A Lactol derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-08-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421734-B1 Process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts AASDHPPT, AAAS, AADAT ALDH1A1 538/4885GAA 4084/4885TSHR 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.