Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628742 | 1.00 | BCHE (0.49) | BCHEKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL13058298 | 0.98 | BCHE (0.50) | BCHEKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL1053598 | 0.93 | BCHE (0.50) | BCHEKDM4EALDH1A1HPGDPKM | |
| SCHEMBL1289738 | 0.88 | ALDH1A1 (0.47) | BCHEKDM4EALDH1A1HPGDPKM | |
| SCHEMBL21322829 | 0.88 | CNR2 (0.47) | BCHEKDM4EALDH1A1HPGDCNR2 | |
| Hydrochloric Acid SCHEMBL1289689 | 0.86 | ALDH1A1 (0.46) | BCHEKDM4EALDH1A1HPGDPKM | |
| SCHEMBL22447850 | 0.85 | KDM4E (0.40) | BCHEKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL22447953 | 0.85 | KDM4E (0.40) | BCHEKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL13676231 | 0.83 | BCHE (0.53) | BCHEKDM4EALDH1A1CNR2CES2 | |
| SCHEMBL13201334 | 0.80 | ALDH1A1 (0.43) | BCHEKDM4EALDH1A1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ABBVIE INC. | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ENPP1, ENPP3, ENPEP | BCHE 543/4885KDM4E 3935/4885ALDH1A1 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.