SCHEMBL21364151

SCHEMBL21364151

c1ccc2c(c1)ccc1c3cn4c(cc3[nH]c21)nc1ccccc14

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.48
ALDH1A1 P00352 4/20 0.36
CYP1A2 P05177 2/20 0.36
MAPT P10636 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP1A1 P04798 1/20 0.36
KEAP1 Q14145 1/20 0.36
CYP1B1 Q16678 1/20 0.36
KDM4E B2RXH2 3/20 0.36
HPGD P15428 3/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALK Q9UM73 1/20 0.35
RAB9A P51151 2/20 0.33
NQO2 P16083 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21622770 0.82 AHR (0.44) KIF11ALDH1A1CYP1A2MAPTCYP2C9
SCHEMBL21622772 0.72 AHR (0.46) KIF11ALDH1A1CYP1A2MAPTCYP2C9
SCHEMBL12240628 0.72 KIF11 (0.74) KIF11ALDH1A1CYP1B1KDM4EHPGD
SCHEMBL14733703 0.69 ESR1 (0.46) KIF11ALDH1A1MAPTKDM4EHPGD
SCHEMBL30933408 0.69 ALDH1A1 (0.49) ALDH1A1CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL20659826 0.69 KIF11 (0.69) KIF11ALDH1A1MAPTCYP1B1KDM4E
SCHEMBL29402876 0.69 KIF11 (0.69) KIF11ALDH1A1MAPTCYP1B1KDM4E
SCHEMBL2850004 0.69 ALDH1A1 (0.49) ALDH1A1CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL23917410 0.68 ALDH1A1 (0.36) ALDH1A1CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL21622865 0.68 ALDH1A1 (0.42) ALDH1A1CYP1A2MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019177243-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2019-09-19 WO disclosed