Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 8/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23996427 | 0.83 | LIMK1 (0.49) | LIMK1CDK5CDK5R1ALOX5HTR2C | |
| SCHEMBL24589835 | 0.83 | LIMK1 (0.49) | LIMK1CDK5CDK5R1ALOX5HTR2C | |
| SCHEMBL24589833 | 0.81 | LIMK1 (0.60) | LIMK1CDK5CLK1PIK3CAEGFR | |
| SCHEMBL18232948 | 0.80 | LIMK1 (0.49) | LIMK1CDK5CDK5R1ALOX5HTR2C | |
| SCHEMBL22874230 | 0.80 | LIMK1 (0.54) | LIMK1CDK5CDK5R1CLK1HTR2C | |
| SCHEMBL18232947 | 0.79 | LIMK1 (0.54) | LIMK1CLK1PIK3CAPIM1PIM2 | |
| SCHEMBL18252205 | 0.78 | LIMK1 (0.41) | LIMK1ALOX5CLK1PIM1PIM2 | |
| SCHEMBL27174136 | 0.78 | GPR3 (0.54) | LIMK1CDK5CDK5R1CLK1KRAS | |
| SCHEMBL149872 | 0.78 | GPR3 (0.54) | LIMK1CDK5CDK5R1CLK1KRAS | |
| SCHEMBL18232869 | 0.78 | ALOX5 (0.34) | LIMK1ALOX5PIM1PIM2GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190288219-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190288219-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | VDAC1, EPCAM, LAGE3 | LIMK1 321/4885CDK5 2699/4885CDK5R1 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.