Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21365347 | 0.91 | CYP2A6 (0.46) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL16356777 | 0.91 | MAOA (0.38) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL5028455 | 0.89 | MAOA (0.39) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL24493021 | 0.89 | MAOA (0.42) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL21450716 | 0.89 | MAPT (0.44) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL16356773 | 0.88 | MAOA (0.36) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL24493047 | 0.87 | CYP19A1 (0.40) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL16356770 | 0.87 | CYP2A6 (0.47) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL22428445 | 0.86 | MAOA (0.43) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL17264919 | 0.85 | MAOA (0.36) | MKNK1MKNK2MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190288219-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190288219-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | VDAC1, EPCAM, LAGE3 | MKNK1 2808/4885MKNK2 3622/4885MEN1 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.