SCHEMBL5028455

SCHEMBL5028455

c1cc(-c2cccc(-n3c4ccncc4c4cnccc43)c2)cc(-n2c3ccncc3c3cnccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.39
MAOB P27338 4/20 0.39
ACHE P22303 1/20 0.39
TNF P01375 1/20 0.39
MEN1 O00255 1/20 0.37
PSIP1 O75475 1/20 0.37
AXL P30530 1/20 0.37
MKNK1 Q9BUB5 1/20 0.37
MKNK2 Q9HBH9 1/20 0.37
CYP1A2 P05177 1/20 0.37
METAP2 P50579 1/20 0.37
ALDH1A1 P00352 1/20 0.37
FGFR1 P11362 1/20 0.37
MAPT P10636 1/20 0.36
DYRK1A Q13627 1/20 0.36
RPS6KA5 O75582 1/20 0.36
KCNH2 Q12809 1/20 0.35
AOC3 Q16853 1/20 0.35
ATM Q13315 2/20 0.35
GRM5 P41594 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16356777 0.98 MAOA (0.38) MAOAMAOBACHETNFMEN1
SCHEMBL16356773 0.95 MAOA (0.36) MAOAMAOBACHETNFMEN1
SCHEMBL17264919 0.95 MAOA (0.36) MAOAMAOBACHETNFMEN1
SCHEMBL17264890 0.94 AOC3 (0.38) MAOAMAOBACHETNFMEN1
SCHEMBL23438633 0.91 ATM (0.49) MAOAMAOBACHETNFCYP1A2
SCHEMBL5030873 0.91 MAOA (0.42) MAOAMAOBACHECYP1A2METAP2
SCHEMBL30322640 0.89 MAOA (0.46) MAOAMAOBACHETNFCYP1A2
SCHEMBL21365348 0.89 MKNK1 (0.44) MEN1PSIP1AXLMKNK1MKNK2
SCHEMBL12162410 0.86 MAPK10 (0.40) MAOAMAOBACHETNFMEN1
SCHEMBL21481446 0.86 KDM4E (0.44) MAOAMAOBACHETNFMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972802-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2018-05-15 US disclosed
US-9972802-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2018-05-15 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9437833-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2016-09-06 US disclosed
US-9437833-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2016-09-06 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20150076469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-03-19 US disclosed
US-20150076469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-03-19 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20120326601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-12-27 US disclosed
US-20120326601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-12-27 US disclosed
US-20120261654-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-10-18 US disclosed
US-20120261654-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-10-18 US disclosed
US-20120193619-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-02 US disclosed
US-20120193619-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-02 US disclosed
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL MAOA 71/4885MAOB 36/4885ACHE 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.