Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547859 | 0.81 | ALDH1A1 (0.35) | CES1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21547850 | 0.78 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL21366188 | 0.75 | CNR2 (0.32) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL21366195 | 0.74 | CFTR (0.37) | CES1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21366309 | 0.73 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL21366406 | 0.72 | CES1 (0.34) | CES1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL21366416 | 0.71 | F2 (0.34) | KDM4EALDH1A1HSD17B10RAF1 | |
| SCHEMBL21366414 | 0.71 | NPSR1 (0.39) | KDM4EALDH1A1HSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL21547807 | 0.70 | ALDH1A1 (0.35) | CES1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21366255 | 0.69 | PIK3CG (0.41) | CES1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | CES1 1597/4885KDM4E 2566/4885ALDH1A1 488/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | CES1 884/4885KDM4E 2197/4885ALDH1A1 630/4885 |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | CES1 1476/4885KDM4E 2472/4885ALDH1A1 488/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | CES1 884/4885KDM4E 2197/4885ALDH1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.