Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21366413 | 0.78 | CYP3A4 (0.36) | ALDH1A1MAPTKDM4EKMT2ANPC1 | |
| SCHEMBL21366422 | 0.76 | SMN1; SMN2 (0.41) | MAPTKDM4EKMT2ANPC1MEN1 | |
| SCHEMBL25605109 | 0.75 | NPSR1 (0.43) | NPSR1ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL20320394 | 0.75 | NPSR1 (0.43) | NPSR1ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL7915881 | 0.73 | NPSR1 (0.41) | NPSR1ALDH1A1MAPTHSD17B10F2 | |
| SCHEMBL10838902 | 0.73 | NPSR1 (0.41) | NPSR1ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL5391630 | 0.73 | NPSR1 (0.41) | NPSR1ALDH1A1MAPTHSD17B10F2 | |
| SCHEMBL21366056 | 0.72 | NPSR1 (0.40) | NPSR1ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL21366409 | 0.71 | CES1 (0.32) | NPSR1RAF1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL21366406 | 0.71 | CES1 (0.34) | NPSR1RAF1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | NPSR1 157/4885RAF1 739/4885ALDH1A1 488/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | NPSR1 104/4885RAF1 1224/4885ALDH1A1 630/4885 |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | NPSR1 178/4885RAF1 647/4885ALDH1A1 488/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | NPSR1 104/4885RAF1 1224/4885ALDH1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.