Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21366414 | 0.78 | NPSR1 (0.39) | PKMKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL21366422 | 0.76 | SMN1; SMN2 (0.41) | KDM4ERAB9ANPC1KMT2AMAPT | |
| SCHEMBL20320399 | 0.75 | ALDH1A1 (0.34) | CYP3A4POLBPLK1KDM4ERAB9A | |
| SCHEMBL25093838 | 0.70 | TLR7 (0.31) | RAB9ANPC1 | |
| SCHEMBL2393111 | 0.67 | HDAC2 (0.39) | PLK1KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL12321713 | 0.67 | CNR2 (0.33) | POLBPKMUSP2CNR2 | |
| SCHEMBL17664669 | 0.67 | HDAC6 (0.41) | PLK1ALDH1A1NPC1CYP1A2 | |
| SCHEMBL21133751 | 0.66 | POLB (0.46) | CYP3A4POLBPKMPLK1KDM4E | |
| SCHEMBL10253784 | 0.66 | HPGD (0.51) | CYP3A4POLBKDM4ERAB9ANPC1 | |
| SCHEMBL6123591 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | CYP3A4 991/4885POLB 4386/4885PKM 4141/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | CYP3A4 394/4885POLB 3538/4885PKM 3907/4885 |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | CYP3A4 774/4885POLB 4371/4885PKM 4036/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | CYP3A4 394/4885POLB 3538/4885PKM 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.