Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21367030 | 1.00 | USP2 (0.45) | USP2L3MBTL1NPSR1RCE1SYK | |
| SCHEMBL21367029 | 0.85 | ABCB1 (0.43) | L3MBTL1RCE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14209809 | 0.83 | TSHR (0.50) | L3MBTL1RCE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1776277 | 0.77 | SMN1; SMN2 (0.43) | L3MBTL1RCE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL26226870 | 0.76 | LTA4H (0.40) | NPSR1SYKPPARACTSS | |
| SCHEMBL5492424 | 0.76 | SLC1A1 (0.50) | SYKPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8092704 | 0.75 | SYK (0.41) | USP2NPSR1SYKPPARASLC1A3 | |
| SCHEMBL6154700 | 0.75 | SYK (0.45) | L3MBTL1SYKPPARAKMT2A | |
| SCHEMBL16370105 | 0.74 | SLC1A3 (0.39) | L3MBTL1RCE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22490406 | 0.74 | MEN1 (0.40) | L3MBTL1RCE1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019177873-A1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2019-09-19 | — | — | WO | disclosed |