Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 6/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19341934 | 0.96 | CTSS (0.55) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL18257518 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL18257539 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL18257552 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL18257560 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL18257543 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL21367482 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL20825306 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL84549 | 0.93 | REN (0.60) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL18941938 | 0.89 | CTSS (0.57) | CTSSCTSKCTSLCTSBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800809-B2 | Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof | LAURUS LABS LIMITED (IN) | 2020-10-13 | — | — | US | disclosed |
| US-20190284231-A1 | PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LIMITED (IN) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800809-B2 | Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof | SF3B5, PRCP, GBA1 | CTSS 132/4885CTSK 252/4885CTSL 81/4885 |
| US-20190284231-A1 | PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SF3B5, PRCP, GBA1 | CTSS 132/4885CTSK 252/4885CTSL 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.