SCHEMBL2136773

SCHEMBL2136773

C=CS(=O)(=O)CCCCCCS(=O)(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
S1PR2 O95136 1/20 0.35
S1PR4 O95977 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
XBP1 P17861 1/20 0.35
S1PR1 P21453 1/20 0.35
MAPK1 P28482 1/20 0.35
AGTR1 P30556 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
FAAH O00519 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2135110 1.00 NPC1 (0.35) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL776640 0.97 NPC1 (0.36) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL1283388 0.90 NPC1 (0.36) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL10639166 0.87 FAAH (0.50) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL11336707 0.87 FAAH (0.50) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL22894669 0.87 FAAH (0.50) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL11325650 0.87 FAAH (0.50) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL11333957 0.87 FAAH (0.50) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL7756252 0.86 NPC1 (0.31) NPC1S1PR2S1PR4ALDH1A1LMNA
SCHEMBL27451940 0.85 TSHR (0.41) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 US disclosed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 US disclosed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 US disclosed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 US disclosed
US-20160311934-A1 HYDROXYALKYL STARCH DERIVATIVES AS REACTANTS FOR COUPLING TO THIOL GROUPS FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2016-10-27 US disclosed
US-20160311934-A1 HYDROXYALKYL STARCH DERIVATIVES AS REACTANTS FOR COUPLING TO THIOL GROUPS FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2016-10-27 US disclosed
EP-2635442-B1 TRANSPARENT INK-JET RECORDING FILMS CARESTREAM HEALTH INC (US) 2015-11-25 EP disclosed
EP-2629981-B1 TRANSPARENT INK- JET RECORDING FILMS CARESTREAM HEALTH INC (US) 2015-08-05 EP disclosed
US-8895965-B2 Photoelectric conversion element, production method for a photoelectric conversion element, solid-state image sensor, production method for a solid-state image sensor, electronic apparatus, photoconductor, production method for a photoconductor and multilayer transparent photoelectric conversion element SONY CORPORATION (JP) 2014-11-25 US disclosed
US-8895965-B2 Photoelectric conversion element, production method for a photoelectric conversion element, solid-state image sensor, production method for a solid-state image sensor, electronic apparatus, photoconductor, production method for a photoconductor and multilayer transparent photoelectric conversion element SONY CORPORATION (JP) 2014-11-25 US disclosed
WO-2012058347-A1 TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS CARESTREAM HEALTH, INC. (US) 2012-05-03 WO disclosed
US-20120107528-A1 TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS QUANTUM MEDICAL IMAGING, L.L.C. 2012-05-03 US disclosed
WO-2012058354-A1 TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS CARESTREAM HEALTH, INC. (US) 2012-05-03 WO disclosed
US-20120107532-A1 TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS CARESTREAM DENTAL LLC 2012-05-03 US disclosed
US-20120107529-A1 TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS QUANTUM MEDICAL IMAGING, L.L.C. 2012-05-03 US disclosed
US-20120100315-A1 TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS CARESTREAM DENTAL LLC 2012-04-26 US disclosed
US-20100092872-A1 NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY USING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-04-15 US disclosed
EP-2138481-A1 NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY USING THE SAME Ube Industries, Ltd. (JP) 2009-12-30 EP disclosed
US-7589070-B2 Surface modification for improving biocompatibility THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2009-09-15 US disclosed
US-RE29305-E HARDENABLE HYDROPHILIC COLLOIDS, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160311934-A1 HYDROXYALKYL STARCH DERIVATIVES AS REACTANTS FOR COUPLING TO THIOL GROUPS MSR1, C3AR1, C1R NPC1 3961/4885S1PR2 562/4885S1PR4 971/4885
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES PAM, UACA, FLT1 NPC1 4774/4885S1PR2 2372/4885S1PR4 2137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.