SCHEMBL21368098

SCHEMBL21368098

CC1(C)c2ccccc2-c2c(N(c3ccc(-c4ccc5c6c(cccc46)-c4ccccc4-5)cc3)c3ccc(-c4cccc5c4oc4ccccc45)cc3)cccc21

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
PRKDC P78527 1/20 0.31
GGPS1 O95749 1/20 0.31
MEN1 O00255 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21368121 0.95 ALOX5 (0.34) ALOX5
SCHEMBL21368351 0.94 ALOX5 (0.38) ALOX5PRKDCGGPS1
SCHEMBL16858158 0.94 ALOX5 (0.43) ALOX5PRKDCGGPS1MEN1CYP2C19
SCHEMBL21368523 0.94 ALOX5 (0.37) ALOX5PRKDCGGPS1
SCHEMBL21368522 0.94 ALOX5 (0.39) ALOX5PRKDCGGPS1
SCHEMBL21368113 0.93 ALOX5 (0.36) ALOX5GGPS1
SCHEMBL21446209 0.93 ALOX5 (0.43) ALOX5PRKDCGGPS1MEN1CYP2C19
SCHEMBL23376199 0.92 ALOX5 (0.39) ALOX5PRKDCGGPS1MEN1CYP2C19
SCHEMBL21368313 0.92 PRKDC (0.30) PRKDC
SCHEMBL23376055 0.92 ALOX5 (0.42) ALOX5PRKDCGGPS1MEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11302870-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2022-04-12 US disclosed
US-20190288206-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11302870-B2 Materials for electronic devices EFNA1, PNMT, FLNB ALOX5 2728/4885PRKDC 2494/4885GGPS1 1823/4885
US-20190288206-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, PNMT, FLNB ALOX5 2643/4885PRKDC 2579/4885GGPS1 1723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.