Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | HGF | P14210 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15713488 | 0.90 | PDK2 (0.39) | PDK2 | |
| SCHEMBL18594401 | 0.87 | PDK2 (0.40) | PDK2HDAC1HDAC3HDAC2 | |
| SCHEMBL9916961 | 0.87 | PDK2 (0.47) | PDK2 | |
| SCHEMBL16366420 | 0.86 | PDK2 (0.49) | PDK2 | |
| SCHEMBL25125148 | 0.85 | PDK2 (0.40) | PDK2 | |
| SCHEMBL18020024 | 0.84 | PDK2 (0.45) | PDK2 | |
| SCHEMBL15713467 | 0.84 | PDK2 (0.39) | PDK2 | |
| SCHEMBL29892218 | 0.84 | PDK2 (0.39) | PDK2 | |
| SCHEMBL24078497 | 0.84 | PDK2 (0.40) | PDK2METHGF | |
| SCHEMBL19163603 | 0.83 | PDK2 (0.41) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11302870-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2022-04-12 | — | — | US | disclosed |
| US-20200048207-A1 | COMPOUNDS WITH ARYLAMINE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20190288206-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11302870-B2 | Materials for electronic devices | EFNA1, PNMT, FLNB | PDK2 866/4885HDAC1 3696/4885HDAC3 4586/4885 |
| US-20200048207-A1 | COMPOUNDS WITH ARYLAMINE STRUCTURES | DDT, NAT1, INMT | PDK2 951/4885HDAC1 3617/4885HDAC3 2575/4885 |
| US-20190288206-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, PNMT, FLNB | PDK2 833/4885HDAC1 3647/4885HDAC3 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.