Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10105233 | 0.75 | NPC1 (0.38) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL1822854 | 0.68 | BRD4 (0.41) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL20385007 | 0.67 | NPC1 (0.33) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL16867577 | 0.64 | NPC1 (0.36) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL5175484 | 0.62 | TTR (0.50) | KDM4ENPC1ALDH1A1MAPTHTT | |
| SCHEMBL13061952 | 0.61 | MAPT (0.49) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL10625407 | 0.61 | MAPT (0.46) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL10625415 | 0.61 | MAPT (0.46) | KDM4EMEN1NPC1ALDH1A1POLB | |
| SCHEMBL28531443 | 0.61 | GPR3 (0.48) | KDM4ENPC1ALDH1A1MAPTHTT | |
| SCHEMBL19792450 | 0.59 | TTR (0.47) | KDM4EMEN1NPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174139-A1 | N-SUBSTITUTED DIBENZOCARBAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 大连理工大学 | 2019-09-19 | — | — | WO | disclosed |