SCHEMBL2137125

SCHEMBL2137125

O=C(Cl)Oc1ccccc1-c1ccccc1OC(=O)Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 2/20 0.39
FABP3 P05413 2/20 0.39
FABP5 Q01469 2/20 0.39
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 3/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
TSHR P16473 1/20 0.36
GGT1 P19440 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860065 0.90 TOP1 (0.35) FABP7FABP3FABP5ALDH1A1KMT2A
SCHEMBL5696260 0.87 SERPINE1 (0.43) ALDH1A1KMT2AKDM4EHSD17B10MAPT
SCHEMBL30524282 0.87 SERPINE1 (0.43) ALDH1A1KMT2AKDM4EHSD17B10MAPT
SCHEMBL29922550 0.87 FABP3 (0.53) FABP7FABP3FABP5ALDH1A1KMT2A
SCHEMBL6220741 0.87 FABP3 (0.53) FABP7FABP3FABP5ALDH1A1KMT2A
SCHEMBL2402122 0.81 TOP1 (0.41) ALDH1A1KMT2AKDM4EMAPTHPGD
SCHEMBL695666 0.79 PTK2B (0.50) ALDH1A1KMT2AMAPTHPGDTDP1
SCHEMBL27601473 0.79 GAA (0.50) ALDH1A1KMT2AKDM4EHSD17B10MAPT
SCHEMBL7017642 0.78 FABP3 (0.44) FABP7FABP3FABP5ALDH1A1KMT2A
SCHEMBL965339 0.77 TDP1 (0.47) ALDH1A1KMT2AKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470957-B2 Method for producing bischloroformate compound, polycarbonate oligomer having small number of monomers and solution containing bischloroformate compound IDEMITSU KOSAN CO., LTD. (JP) 2013-06-25 US disclosed
US-20130066037-A1 METHOD FOR PRODUCING BISCHLOROFORMATE COMPOUND, POLYCARBONATE OLIGOMER HAVING SMALL NUMBER OF MONOMERS AND SOLUTION CONTAINING BISCHLOROFORMATE COMPOUND HIKOSAKA TAKAAKI (JP) 2013-03-14 US disclosed
US-8344092-B2 Method for producing bischloroformate compound, polycarbonate oligomer having small number of monomers and solution containing bischloroformate compound IDEMITSU KOSAN CO., LTD. (JP) 2013-01-01 US disclosed
US-20120101292-A1 METHOD FOR PRODUCING BISCHLOROFORMATE COMPOUND, POLYCARBONATE OLIGOMER HAVING SMALL NUMBER OF MONOMERS AND SOLUTION CONTAINING BISCHLOROFMATE COMPOUND IDEMITSU KOSAN CO. LTD 2012-04-26 US disclosed
US-5043413-A Low birefringence polyarylate from polyarylene dicarboxylic acid and polyarylene diphenol UNITIKA LTD. (JP) 1991-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101292-A1 METHOD FOR PRODUCING BISCHLOROFORMATE COMPOUND, POLYCARBONATE OLIGOMER HAVING SMALL NUMBER OF MONOMERS AND SOLUTION CONTAINING BISCHLOROFMATE COMPOUND FHIT, RCC1, PCNA FABP7 3286/4885FABP3 3597/4885FABP5 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.