SCHEMBL21372

SCHEMBL21372

Nc1ccc(-c2ccc(N)cc2N)c(N)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 4/20 0.52
TSHR P16473 4/20 0.46
POLB P06746 3/20 0.46
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
ALDH1A1 P00352 8/20 0.44
CYP3A4 P08684 6/20 0.44
TDP1 Q9NUW8 5/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TP53 P04637 1/20 0.44
MAPK1 P28482 1/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
MAPT P10636 4/20 0.44
LMNA P02545 4/20 0.42
PTPRC P08575 2/20 0.42
HPGD P15428 2/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5983366 1.00 CASP1 (0.52) CASP1TSHRPOLBGAAGLA
Hydrochloric Acid SCHEMBL134928 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
SCHEMBL9451786 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
SCHEMBL4339277 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
Hydrochloric Acid SCHEMBL992773 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
Hydrochloric Acid SCHEMBL999546 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
Hydrochloric Acid SCHEMBL592948 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
Water SCHEMBL7066179 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
SCHEMBL5065507 0.97 CASP1 (0.50) CASP1TSHRPOLBGAAGLA
Hydrochloric Acid SCHEMBL3504242 0.94 CASP1 (0.48) CASP1TSHRPOLBGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 31473 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119986006-B Application of reagent for detecting GYSY-1 polypeptide in preparation of products for prognosis of colon cancer and evaluation of sensitivity of immunotherapy THE THIRD AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL University (GUANGZHOU SEVERE MATERNAL RESCUE CENTER GUANGZHOU ROUJI HOSPITAL) (CN) 2026-05-26 CN claimed
EP-4211663-B1 A SCORING METHOD FOR AN ANTI-B7H4 ANTIBODY-DRUG CONJUGATE THERAPY MEDIMMUNE LTD (GB) 2026-02-18 EP claimed
EP-3684846-B1 PROCESS FOR PREPARING POLYBENZIMIDAZOLES UNIV WIEN TECH (AT) 2026-01-14 EP claimed
EP-4211598-B1 A SCORING METHOD FOR AN ANTI-HER2 ANTIBODY-DRUG CONJUGATE THERAPY ASTRAZENECA UK LTD (GB) 2026-01-07 EP claimed
US-20250354204-A1 AUTOMATED RNA DETECTION USING LABELED 2'-O-METHYL RNA OLIGONUCLEOTIDE PROBES AND SIGNAL AMPLIFICATION SYSTEMS VENTANA MED SYST INC (US) 2025-11-20 US claimed
US-12466894-B2 Anti-MUC16 antibodies and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-11-11 US claimed
EP-4621411-A1 METHOD FOR DETECTING SIALYLATED IGE Leti Pharma S.L. (ES) 2025-09-24 EP claimed
US-20250252572-A1 METHOD, SYSTEM, AND COMPUTER-READABLE RECORDING MEDIA FOR PROCESSING TISSUE IMAGES JelloX Biotech Inc. (TW) 2025-08-07 US claimed
CN-118491316-B High-temperature-resistant nanofiltration membrane based on rigid amine monomer, and preparation method and application thereof 浙江大学 2025-06-24 CN claimed
CN-120142648-A Small molecule immunodetection kit and small molecule immunodetection method 中国农业科学院蔬菜花卉研究所 2025-06-13 CN claimed
US-4610947-A Method and manufacturing polyimidazole and polyimidazopyrrolone relief structures SIEMENS AKTIENGESELLSCHAFT (DE) 1986-09-09 US claimed
WO-1986004610-A1 STABILIZED ENZYME SUBSTRATE SOLUTIONS TRAVENOL-GENENTECH DIAGNOSTICS (US) 1986-08-14 WO claimed
EP-0157931-A1 Process for preparing precursors of polyimidazoles and polyimidazo pyrrolones SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP claimed
EP-0157932-A1 Process for the preparation of polyimidazole and polyimidazopyrrolone relief structures SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP claimed
US-4397999-A TETRAAMINO AROMATIC COMPOUND, DICARBOXYLIC ACID, AND GLYCIDYL ACRYLATE OR METHACRYLATE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-08-09 US claimed
EP-0024592-B1 POLYIMIDAZOLES AND POLYIMIDAZOPYRROLONE PRECURSORS AND THEIR PREPARATION SIEMENS AKTIENGESELLSCHAFT (DE) 1983-06-01 EP claimed
EP-0026299-B1 METHOD OF PRODUCING HEAT RESISTANT RELIEF STRUCTURES, RELIEF STRUCTURES PRODUCED THEREBY AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-04-20 EP claimed
US-4332882-A POLYIMIDAZOLES AND POLYIMIDAZOPYRROLONES SIEMENS AKTIENGESELLSCHAFT (DE) 1982-06-01 US claimed
EP-0026299-A1 Method of producing heat resistant relief structures, relief structures produced thereby and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-04-08 EP claimed
EP-0024592-A1 Polyimidazoles and polyimidazopyrrolone precursors and their preparation SIEMENS AKTIENGESELLSCHAFT (DE) 1981-03-11 EP claimed