Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 3/20 | 0.44 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.44 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.41 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL592948 | 1.00 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL999546 | 1.00 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL992773 | 1.00 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL3504242 | 0.97 | CASP1 (0.48) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL5983366 | 0.97 | CASP1 (0.52) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL21372 | 0.97 | CASP1 (0.52) | CASP1TSHRPOLBGAAGLA | |
| Water SCHEMBL7066179 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL9451786 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL5065507 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL4339277 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1855 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118533806-A | Research method for water flooding resistant molecular characteristics of super arundo donax | 郑州大学 | 2024-08-23 | — | — | CN | claimed |
| WO-2021111461-A1 | NANOZYME LINKED OLIGO PROBE SORBENT ASSAY (NLOPSA) FOR THE DETECTION OF NUCLEIC ACID BIOMARKERS | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT Madras) (IN) | 2021-06-10 | — | — | WO | claimed |
| US-10557851-B2 | Signaling conjugates and methods of use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-02-11 | — | — | US | claimed |
| US-20170199179-A1 | PD-IR NANOPARTICLES USED AS PEROXIDASE MIMICS | MICHIGAN TECHNOLOGICAL UNIVERSITY | 2017-07-13 | — | — | US | claimed |
| EP-3096140-A1 | NANOMETER MIMIC ENZYME IMMUNOCHROMATOGRAPHY DETECTION METHOD | The Institute of Biophysics Chinese Academy of Sciences (CN) | 2016-11-23 | — | — | EP | claimed |
| US-20160334397-A1 | NANOZYME IMMUNOCHROMATOGRAPHIC DETECTION METHOD | GILL BIOTECHNOLOGY (TIANJIN) CO., LTD., (CN) | 2016-11-17 | — | — | US | claimed |
| US-20160103044-A1 | DEVICES AND METHODS FOR DIAGNOSING, PROGNOSING, OR THERANOSING A CONDITION BY ENRICHING RARE CELLS | FIRST-CITIZENS BANK & TRUST COMPANY | 2016-04-14 | — | — | US | claimed |
| EP-2898329-A1 | METHOD OF IDENTIFYING TREATMENT RESPONSIVE NON-SMALL CELL LUNG CANCER USING ANAPLASTIC LYMPHOMA KINASE (ALK) AS A MARKER | Ventana Medical Systems, Inc. (US) | 2015-07-29 | — | — | EP | claimed |
| WO-2014046730-A1 | METHOD OF IDENTIFYING TREATMENT RESPONSIVE NON-SMALL CELL LUNG CANCER USING ANAPLASTIC LYMPHOMA KINASE (ALK) AS A MARKER | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-03-27 | — | — | WO | claimed |
| EP-2596119-A2 | METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS | Advanced Cell Technology, Inc. (US) | 2013-05-29 | — | — | EP | claimed |
| US-20030068076-A1 | Method and apparatus for scoring the uptake of markers in cells | CARL ZEISS MICROSCOPY GMBH (DE) | 2003-04-10 | — | — | US | claimed |
| EP-1198556-A2 | METHODS FOR PRODUCING AND PREPARING CELLS FOR CELL THERAPY | Neurotrophic Bioscience, Inc. (CA) | 2002-04-24 | — | — | EP | claimed |
| WO-2001005940-A2 | METHODS FOR PRODUCING AND PREPARING CELLS FOR CELL THERAPY | NEUROTROPHIC BIOSCIENCE, INC. (CA) | 2001-01-25 | — | — | WO | claimed |
| EP-0975973-A1 | METHOD FOR DETERMINING THE PRESENCE OF MUTATED BRCA PROTEIN | Baystate Medical Center (US) | 2000-02-02 | — | — | EP | claimed |
| US-5965377-A | SCREENING FOR SUSCEPTIBILITY TO BREAST AND OVARIAN CANCER; USING AN ANTIBODY BASED METHOD, TARGETING SPECIFIC CARBOXY-TERMINUS MUTATIONS IN PROTEIN EXPRESSED IN EPITHELIAL CELLS, MEASURING ANTIBODY REACTIVITY WITH PROTEIN | BAYSTATE MEDICAL CENTER (US) | 1999-10-12 | — | — | US | claimed |
| WO-1998043092-A1 | METHOD FOR DETERMINING THE PRESENCE OF MUTATED BRCA PROTEIN | BAYSTATE MEDICAL CENTER (US) | 1998-10-01 | — | — | WO | claimed |
| EP-0618300-A1 | TMB formulation for soluble and precipitable HRP-ELISA | BioVest, Inc. (US) | 1994-10-05 | — | — | EP | claimed |
| EP-0456782-A1 | TMB FORMULATION FOR SOLUBLE AND PRECIPITABLE HRP-ELISA. | TSI CORP (US) | 1991-11-21 | — | — | EP | claimed |
| WO-1991006672-A1 | TMB FORMULATION FOR SOLUBLE AND PRECIPITABLE HRP-ELISA | TSI-MASON RESEARCH INSTITUTE (US) | 1991-05-16 | — | — | WO | claimed |
| US-5006461-A | Chromogens forms stable precipitate with polymer | TRANSGENIC SCIENCES, INC. (US) | 1991-04-09 | — | — | US | claimed |