Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372 | 0.97 | CASP1 (0.52) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL5983366 | 0.97 | CASP1 (0.52) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL592948 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL9451786 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL992773 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| SCHEMBL4339277 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL999546 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Water SCHEMBL7066179 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL134928 | 0.94 | CASP1 (0.50) | CASP1TSHRPOLBGAAGLA | |
| Hydrochloric Acid SCHEMBL3504242 | 0.91 | CASP1 (0.48) | CASP1TSHRPOLBGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187917-A1 | Compositions and methods for repressing the Ink4a and Arf senescence pathways | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-08-07 | — | — | US | disclosed |
| WO-2007100576-A2 | COMPOSITIONS AND METHODS FOR REPRESSING THE INK4A AND ARF SENESCENCE PATHWAYS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2005032580-A1 | METHODS AND COMPOSITIONS FOR TREATING EOSINOPHIL MEDIATED GASTRO-INTESTINAL DYSFUNCTION OR DISEASE | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2005-04-14 | — | — | WO | disclosed |
| US-20050032129-A1 | Detection of antigen by immunohistochemical staining | KAGOSHIMA UNIVERSITY (JP) | 2005-02-10 | — | — | US | disclosed |