Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135528 | 0.90 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPK1SYKCHRM2 | |
| SCHEMBL418232 | 0.85 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1SYKCA1 | |
| SCHEMBL5557245 | 0.84 | CA1 (0.51) | ALDH1A1L3MBTL1MAPK1SYKCA1 | |
| SCHEMBL7737502 | 0.84 | CA1 (0.51) | ALDH1A1L3MBTL1MAPK1SYKCA1 | |
| SCHEMBL8134806 | 0.84 | SYK (0.40) | ALDH1A1L3MBTL1MAPK1SYKCHRM2 | |
| SCHEMBL27425114 | 0.84 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1SYKLMNA | |
| SCHEMBL8132756 | 0.83 | SYK (0.40) | ALDH1A1L3MBTL1MAPK1SYKCHRM2 | |
| SCHEMBL18515899 | 0.83 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPK1SYKCA1 | |
| SCHEMBL3903941 | 0.82 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1MAPK1SYKLMNA | |
| SCHEMBL23205643 | 0.82 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20120101137-A1 | NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101137-A1 | NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | GCK, GCKR, HK2 | ALDH1A1 2623/4885L3MBTL1 4632/4885MAPK1 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.