Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.52 |
| ▸ | HMGCR | P04035 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302031 | 0.81 | PTPN7 (0.70) | PTPN7HMGCRMAPTKMT2ARECQL | |
| Bicarbonate SCHEMBL873829 | 0.80 | HMGCR (0.57) | PTPN7HMGCRMAPTKMT2ARECQL | |
| SCHEMBL11300915 | 0.79 | PTPN7 (0.68) | PTPN7HMGCRMAPTKMT2ARECQL | |
| SCHEMBL8465449 | 0.79 | KMT2A (0.67) | MAPTKMT2ATDP1MEN1ALDH1A1 | |
| SCHEMBL9746172 | 0.78 | KMT2A (0.50) | PTPN7HMGCRMAPTKMT2ATDP1 | |
| Bicarbonate SCHEMBL30656137 | 0.78 | PTPN7 (0.61) | PTPN7HMGCRMAPTKMT2ARECQL | |
| Acetic Acid SCHEMBL28886472 | 0.78 | HMGCR (0.55) | PTPN7HMGCRMAPTKMT2ARECQL | |
| Bicarbonate SCHEMBL874695 | 0.78 | PTPN7 (0.61) | PTPN7HMGCRMAPTKMT2ARECQL | |
| SCHEMBL15071853 | 0.78 | CYP1A2 (0.40) | PTPN7HMGCRMAPTKMT2ARECQL | |
| Bicarbonate SCHEMBL28984116 | 0.78 | HMGCR (0.50) | PTPN7HMGCRMAPTKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180105-A1 | MITOCHONDRIAL PH PROBE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-09-26 | — | — | WO | disclosed |
| EP-3543705-A1 | MITOCHONDRIAL PH PROBE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-09-25 | — | — | EP | disclosed |