Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL874695 | 0.98 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| Bicarbonate SCHEMBL30656137 | 0.98 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| Bicarbonate SCHEMBL28077752 | 0.96 | PTPN7 (0.59) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| Acetic Acid SCHEMBL28886472 | 0.93 | HMGCR (0.55) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| Bicarbonate SCHEMBL28984116 | 0.93 | HMGCR (0.50) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| Bicarbonate SCHEMBL15967833 | 0.87 | PTPN7 (0.71) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| SCHEMBL55920 | 0.87 | — | — | |
| SCHEMBL5167023 | 0.87 | — | — | |
| Bicarbonate SCHEMBL15967786 | 0.85 | PTPN7 (0.75) | HMGCRPTPN7RECQLTDP1ALDH1A1 | |
| Bicarbonate SCHEMBL15967688 | 0.85 | PTPN7 (0.75) | HMGCRPTPN7RECQLTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220364016-A1 | PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2022-11-17 | — | — | US | claimed |
| EP-4025675-A1 | A PERFUME OIL MIXTURE | Symrise AG (DE) | 2022-07-13 | — | — | EP | claimed |
| CN-110179172-B | Consumable for an aerosol-generating device | 菲利普莫里斯生产公司 | 2022-06-24 | — | — | CN | claimed |
| WO-2021043585-A1 | A PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2021-03-11 | — | — | WO | claimed |
| EP-2969027-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND FRAGRANCES | BEIERSDORF AG (DE) | 2020-10-14 | — | — | EP | claimed |
| US-20060166857-A1 | 4,8-Dimethyl-7-nonen-2-one and 4,8-dimethylnonan-2-one used as perfumes | SYMRISE GMBH & CO. KG (DE) | 2006-07-27 | — | — | US | claimed |
| EP-4025675-B1 | A PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2026-03-18 | — | — | EP | disclosed |
| US-12421474-B2 | Perfume oil mixture | SYMRISE AG (DE) | 2025-09-23 | — | — | US | disclosed |
| CN-115103719-B | Encapsulated fragrance based on natural amino acids | 西姆莱斯股份公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-113766969-B | Method for preparing microcapsules | 西姆莱斯股份公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116322327-A | Method for preparing microcapsules | 西姆莱斯股份公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20220364016-A1 | PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2022-11-17 | — | — | US | disclosed |
| CN-115103719-A | Encapsulated fragrance based on natural amino acids | 西姆莱斯股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-1561476-A1 | DEODORANT COMPOSITION | Takasago International Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |
| US-20050154133-A1 | Polymer mixtures with improved odor control | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | US | disclosed |
| US-20040249079-A1 | Highly swellable hydrogels with acid centers | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-09 | — | — | US | disclosed |
| US-20040180189-A1 | Acidic superabsorbent hydrogels | BASF AKTIENGESELLSCHAFT, A GERMAN CORPORATION (DE) | 2004-09-16 | — | — | US | disclosed |
| US-5538943-A | Use of 1,3-undecadien-5-yne as a perfuming ingredient | FIRMENICH SA (CH) | 1996-07-23 | — | — | US | disclosed |
| US-5180710-A | ETHYL (2E,4Z,7Z)-2,4,7-DECATRIENOATE AND ITS USE AS A PERFUMING OR FLAVORING INGREDIENT | FIRMENICH S.A. (CH) | 1993-01-19 | — | — | US | disclosed |
| US-3969259-A | 2,4,4'-TRICHLORO-2'-HYDROXY DIPHENYL ETHER | LEVER BROTHERS COMPANY (US) | 1976-07-13 | — | — | US | disclosed |