Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 11/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373660 | 0.75 | FGFR1 (0.50) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL28200925 | 0.75 | FGFR1 (0.54) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL1318366 | 0.73 | FGFR1 (0.55) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL20385993 | 0.71 | FGFR1 (0.55) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL21373604 | 0.70 | QPCT (0.37) | KDM4EMAPT | |
| SCHEMBL27976107 | 0.69 | CLK1 (0.74) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL21565626 | 0.68 | ABL1 (0.51) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL20380290 | 0.68 | FGFR1 (0.50) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL20386115 | 0.68 | FGFR1 (0.51) | FGFR1FGFR2FGFR3DYRK1AMAPK1 | |
| SCHEMBL2460902 | 0.67 | FGFR1 (1.00) | FGFR1FGFR2FGFR3DYRK1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543231-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2019-09-25 | — | — | EP | claimed |
| EP-3568133-B1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH ZUERICH (CH) | 2023-12-13 | — | — | EP | disclosed |
| CN-116462666-A | Cytoprotective compounds and uses thereof | 瑞士苏黎世联邦理工学院 | 2023-07-21 | — | — | CN | disclosed |
| EP-3543231-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2019-09-25 | — | — | EP | disclosed |