Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 7/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008269 | 0.77 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL31143361 | 0.77 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2810219 | 0.77 | QPCT (0.41) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2840581 | 0.76 | QPCT (0.40) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL23123086 | 0.73 | QPCT (0.51) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2474515 | 0.71 | QPCT (0.60) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL15190605 | 0.71 | ALDH1A1 (0.39) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL27601236 | 0.70 | QPCT (0.41) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL21373530 | 0.70 | FGFR1 (0.50) | MAPTKDM4E | |
| SCHEMBL21387779 | 0.70 | QPCT (0.38) | QPCTQPCTLMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543231-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2019-09-25 | — | — | EP | claimed |
| EP-3568133-B1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH ZUERICH (CH) | 2023-12-13 | — | — | EP | disclosed |
| CN-116462666-A | Cytoprotective compounds and uses thereof | 瑞士苏黎世联邦理工学院 | 2023-07-21 | — | — | CN | disclosed |
| EP-3543231-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2019-09-25 | — | — | EP | disclosed |