Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141792 | 0.77 | POLB (0.57) | HDAC1ALDH1A1CYP1A2TSHRPOLB | |
| SCHEMBL30695197 | 0.77 | POLB (0.57) | HDAC1ALDH1A1CYP1A2TSHRPOLB | |
| SCHEMBL21374156 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP1A2TSHRMAPK1POLB | |
| SCHEMBL20154265 | 0.71 | KMT2A (0.45) | ALDH1A1MAPK1MEN1KMT2ARAB9A | |
| SCHEMBL23591218 | 0.69 | KMT2A (0.58) | ALDH1A1MAPK1MEN1KMT2ARAB9A | |
| SCHEMBL537743 | 0.69 | EHMT2 (0.59) | HDAC1HDAC2ALDH1A1CYP1A2POLB | |
| SCHEMBL23937565 | 0.68 | KMT2A (0.60) | ALDH1A1MAPK1MEN1KMT2ARAB9A | |
| SCHEMBL31005447 | 0.67 | POLB (0.74) | HDAC1ALDH1A1CYP1A2POLBMEN1 | |
| SCHEMBL16938383 | 0.67 | POLB (0.74) | HDAC1ALDH1A1CYP1A2POLBMEN1 | |
| SCHEMBL2592282 | 0.67 | CYP1A2 (0.54) | ALDH1A1CYP1A2TSHRMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | HDAC1 3276/4885HDAC2 3776/4885ALDH1A1 4859/4885 |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | HDAC1 3276/4885HDAC2 3776/4885ALDH1A1 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.