⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21431246 | 0.79 | CHRNB2 (0.32) | — | |
| SCHEMBL14269798 | 0.79 | LMNA (0.35) | — | |
| SCHEMBL21374424 | 0.75 | KDM4E (0.30) | — | |
| SCHEMBL26487432 | 0.73 | EPHX1 (0.32) | — | |
| SCHEMBL15703100 | 0.73 | — | — | |
| SCHEMBL15583521 | 0.72 | LMNA (0.39) | — | |
| SCHEMBL23621398 | 0.72 | KISS1R (0.38) | — | |
| SCHEMBL24377857 | 0.72 | — | — | |
| SCHEMBL22413624 | 0.72 | KISS1R (0.38) | — | |
| SCHEMBL21424796 | 0.72 | KISS1R (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11060089-B2 | Antisense oligomers and methods of using the same for treating diseases associated with the acid alpha-glucosidase gene | SAREPTA THERAPEUTICS, INC. (US) | 2021-07-13 | — | — | US | disclosed |
| US-20190284555-A1 | ANTISENSE OLIGOMERS AND METHODS OF USING THE SAME FOR TREATING DISEASES ASSOCIATED WITH THE ACID ALPHA-GLUCOSIDASE GENE | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2019-09-19 | — | — | US | disclosed |