Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376914 | 0.91 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL21376507 | 0.91 | SMN1; SMN2 (0.62) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL662004 | 0.84 | KMT2A (0.76) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL21376786 | 0.83 | ADORA3 (0.59) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21910763 | 0.80 | CFTR (0.46) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL21376793 | 0.79 | MEN1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16607135 | 0.78 | ALDH1A1 (0.76) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL21376589 | 0.77 | AVPR1A (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL16607202 | 0.77 | ALDH1A1 (0.66) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16607184 | 0.77 | ALDH1A1 (0.76) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |