Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376318 | 0.81 | TSHR (0.45) | SRD5A2NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL6830467 | 0.81 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL4059143 | 0.81 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL228477 | 0.81 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL21376784 | 0.80 | CA1 (0.61) | PLA2G4BMAOBNPC1POLBRAB9A | |
| SCHEMBL11273693 | 0.79 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL11603274 | 0.79 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL11603952 | 0.79 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| Hydrochloric Acid SCHEMBL8544438 | 0.79 | NR4A2 (0.96) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL662376 | 0.77 | MEN1 (0.65) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |