Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.60 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.60 |
| ▸ | KDM4A | O75164 | 4/20 | 0.60 |
| ▸ | KDM4B | O94953 | 4/20 | 0.60 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM5C | P41229 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230323 | 0.87 | ADORA3 (0.79) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL21376789 | 0.84 | GRM1 (0.63) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL29379460 | 0.83 | KDM4A (0.64) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL663231 | 0.83 | KDM4A (0.64) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL21376823 | 0.82 | ADORA3 (0.58) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL18230436 | 0.79 | GRM1 (0.61) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL18997292 | 0.76 | GRM1 (1.00) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL18997298 | 0.76 | KDM4A (0.72) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL18997305 | 0.76 | ADORA3 (0.87) | ADORA3GRM1KDM4AKDM4BKDM5B | |
| SCHEMBL21376917 | 0.75 | GRM1 (0.76) | ADORA3GRM1KDM4AKDM4BKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |