Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.61 |
| ▸ | KDM4A | O75164 | 1/20 | 0.61 |
| ▸ | KDM4B | O94953 | 1/20 | 0.61 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.61 |
| ▸ | MPL | P40238 | 5/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SCD | O00767 | 1/20 | 0.53 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230323 | 0.89 | ADORA3 (0.79) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL31265595 | 0.85 | PARP1 (0.74) | ADORA3MPLPARP1MEN1MAPT | |
| SCHEMBL26884069 | 0.81 | GSTO1 (0.62) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL18236300 | 0.80 | GRM1 (0.53) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL21376543 | 0.79 | ADORA3 (0.60) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL17107141 | 0.78 | SCD (0.64) | ADORA3KDM4AKDM4BKDM5BPARP1 | |
| SCHEMBL21376789 | 0.77 | GRM1 (0.63) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL663231 | 0.76 | KDM4A (0.64) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL29379460 | 0.76 | KDM4A (0.64) | GRM1ADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL18997292 | 0.76 | GRM1 (1.00) | GRM1ADORA3KDM4AKDM4BKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |