Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376522 | 0.92 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL21376788 | 0.79 | AKR1C3 (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL23677186 | 0.77 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL24286547 | 0.76 | CYP3A4 (0.41) | ALDH1A1GAASMN1; SMN2MGLLSIGMAR1 | |
| SCHEMBL21376787 | 0.72 | AKR1C3 (0.53) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL28558981 | 0.72 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21376785 | 0.71 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL18002501 | 0.71 | HDAC1 (0.51) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL21909800 | 0.70 | ATM (0.44) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL18003041 | 0.68 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |