Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376785 | 0.81 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2AMAPTNOTUM | |
| SCHEMBL21376788 | 0.80 | AKR1C3 (0.54) | SMN1; SMN2MEN1KMT2AMAPTNOTUM | |
| SCHEMBL28558981 | 0.76 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2AMAPTNOTUM | |
| SCHEMBL21909752 | 0.74 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL21376787 | 0.74 | AKR1C3 (0.53) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL665206 | 0.73 | KMT2A (0.74) | MEN1KMT2AMAPTAKR1C3 | |
| SCHEMBL21376579 | 0.70 | MEN1 (0.42) | ATMSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL24286547 | 0.70 | CYP3A4 (0.41) | SMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL21376800 | 0.67 | RAB9A (0.47) | MEN1KMT2AMAPT | |
| SCHEMBL21909803 | 0.67 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |