Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376579 | 0.92 | MEN1 (0.42) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21376787 | 0.77 | AKR1C3 (0.53) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23677186 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18003041 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21376788 | 0.70 | AKR1C3 (0.54) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17969050 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL15651011 | 0.69 | GAA (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21376815 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21376928 | 0.68 | L3MBTL1 (0.61) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24286547 | 0.68 | CYP3A4 (0.41) | ALDH1A1SMN1; SMN2KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |