Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135126 | 0.91 | ALDH1A1 (0.31) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL2138182 | 0.89 | EPHX1 (0.31) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL2135597 | 0.88 | EPHX1 (0.33) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL2135278 | 0.88 | EPHX1 (0.33) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL2134291 | 0.88 | EPHX1 (0.30) | EPHX1 | |
| SCHEMBL2138851 | 0.88 | ALDH1A1 (0.31) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL2136646 | 0.87 | TSHR (0.37) | ALDH1A1TSHREPHX1 | |
| SCHEMBL2133594 | 0.85 | NOS3 (0.36) | EPHX1 | |
| SCHEMBL2136414 | 0.85 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL2134436 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1EPHX1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471252-B | Process for producing (fluoroalkylthio) acetic acid ester | SUMITOMO CHEMICAL CO | 2014-07-02 | — | — | CN | disclosed |
| CN-103709079-A | Process for preparation of (fluoroalkylthio)acetic acid esters | MASAJI HIROTA HIROYUKI MIYAZAKI TADAYOSHI ITOH | 2014-04-09 | — | — | CN | disclosed |
| EP-2664613-A1 | Process for producing amide compounds | Sumitomo Chemical Company, Limited (JP) | 2013-11-20 | — | — | EP | disclosed |
| EP-2662355-A1 | Process for producing a (fluoroalkylthio) acetonitrile | Sumitomo Chemical Company, Limited (JP) | 2013-11-13 | — | — | EP | disclosed |
| EP-2465846-A1 | PROCESS FOR PREPARATION OF (FLUOROALKYLTHIO)ACETIC ACID ESTERS | Sumitomo Chemical Company, Limited (JP) | 2012-06-20 | — | — | EP | disclosed |
| CN-102471252-A | Process for producing (fluoroalkylthio) acetic acid ester | SUMITOMO CHEMICAL CO | 2012-05-23 | — | — | CN | disclosed |
| US-20120101294-A1 | PROCESS FOR PRODUCING (FLUOROALKYLTHIO) ACETIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101294-A1 | PROCESS FOR PRODUCING (FLUOROALKYLTHIO) ACETIC ACID ESTER | GRHPR, AKR7A2, FAR1 | ALDH1A1 41/4885CYP3A4 257/4885ALOX15 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.