Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376641 | 0.91 | ITGB1 (0.42) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL21358738 | 0.91 | L3MBTL1 (0.48) | ANPEPL3MBTL1ITGB1ITGA4NPC1 | |
| SCHEMBL21358736 | 0.91 | L3MBTL1 (0.48) | ANPEPL3MBTL1ITGB1ITGA4NPC1 | |
| SCHEMBL21376637 | 0.90 | PPID (0.45) | ALDH1A1LMNAL3MBTL1ITGB1ITGA4 | |
| SCHEMBL21376372 | 0.88 | NAMPT (0.50) | ALDH1A1LMNAKMT2AHTTL3MBTL1 | |
| SCHEMBL21358730 | 0.86 | PTPN1 (0.54) | ALDH1A1KMT2ACASRL3MBTL1ITGB1 | |
| SCHEMBL21358729 | 0.86 | PTPN1 (0.54) | ALDH1A1KMT2ACASRL3MBTL1ITGB1 | |
| SCHEMBL21376639 | 0.83 | OPRM1 (0.43) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL21376375 | 0.83 | POLB (0.54) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL21376373 | 0.80 | HPGD (0.53) | ALDH1A1LMNAKMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178248-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |