Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | FES | P07332 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358736 | 0.89 | L3MBTL1 (0.48) | SMN1; SMN2 | |
| SCHEMBL21358738 | 0.89 | L3MBTL1 (0.48) | SMN1; SMN2 | |
| SCHEMBL21376372 | 0.89 | NAMPT (0.50) | LMNAKMT2ANAMPTALDH1A1HTT | |
| SCHEMBL21376639 | 0.84 | OPRM1 (0.43) | LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL21376641 | 0.84 | ITGB1 (0.42) | LMNAKMT2AMEN1TDP1NAMPT | |
| SCHEMBL21376638 | 0.83 | ALDH1A1 (0.46) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL21376637 | 0.83 | PPID (0.45) | LMNATDP1NAMPTALDH1A1 | |
| SCHEMBL21358729 | 0.79 | PTPN1 (0.54) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21358730 | 0.79 | PTPN1 (0.54) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21376376 | 0.78 | ITGA4 (0.51) | KMT2AMEN1NAMPTHTTFES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178248-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |