SCHEMBL2137670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12786051	0.91	APP (0.44)	APPAQP1POLBMAPTL3MBTL1
	SCHEMBL12974431	0.90	APP (0.45)	APPAQP1POLBMAPTL3MBTL1
	SCHEMBL2140353	0.89	APP (0.43)	APPAQP1POLBMAPTRAB9A
	SCHEMBL2136110	0.89	APP (0.43)	APPAQP1POLBMAPTL3MBTL1
	SCHEMBL10206317	0.88	APP (0.45)	APPAQP1POLBMAPTRAB9A
	SCHEMBL2138062	0.85	APP (0.42)	APPAQP1POLBMAPTRAB9A
	SCHEMBL11902544	0.85	APP (0.42)	APPAQP1POLBMAPTRAB9A
	SCHEMBL2138077	0.85	APP (0.42)	APPAQP1POLBMAPTRAB9A
	SCHEMBL1610274	0.83	ALDH1A1 (0.42)	APPPOLBMAPTRAB9AL3MBTL1
	SCHEMBL2712090	0.81	APP (0.40)	APPAQP1POLBMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.