Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22902138 | 0.96 | PRMT1 (0.34) | PRMT1ALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL17190557 | 0.90 | STAT3 (0.41) | ALDH1A1MAPK1CYP3A4SMN1; SMN2CA2 | |
| SCHEMBL20182370 | 0.87 | TP53 (0.31) | PRMT1ALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL17190561 | 0.83 | FAAH (0.38) | ALDH1A1KDM4EHPGD | |
| SCHEMBL21846596 | 0.81 | PRMT1 (0.40) | PRMT1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL21846597 | 0.78 | PPARA (0.34) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL22142508 | 0.75 | — | — | |
| SCHEMBL21846601 | 0.75 | PRMT1 (0.33) | PRMT1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL12733507 | 0.74 | CYP3A4 (0.45) | ALDH1A1MAPK1CYP3A4TP53SMN1; SMN2 | |
| SCHEMBL16656516 | 0.73 | STAT3 (0.45) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190284474-A1 | SWITCHING LAYER FOR USE IN AN OPTICAL SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |