Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376714 | 0.96 | PRMT1 (0.36) | PRMT1ALDH1A1TP53MAPK1SMN1; SMN2 | |
| SCHEMBL21846596 | 0.87 | PRMT1 (0.40) | PRMT1ALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL17190557 | 0.87 | STAT3 (0.41) | ALDH1A1MAPK1SMN1; SMN2CYP3A4CA2 | |
| SCHEMBL20182370 | 0.84 | TP53 (0.31) | PRMT1ALDH1A1TP53MAPK1SMN1; SMN2 | |
| SCHEMBL21846597 | 0.82 | PPARA (0.34) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL17190561 | 0.80 | FAAH (0.38) | ALDH1A1KDM4EHPGD | |
| SCHEMBL21892011 | 0.76 | — | — | |
| SCHEMBL17484031 | 0.76 | TERT (0.32) | MAPTSTAT3HIF1A | |
| SCHEMBL21846601 | 0.74 | PRMT1 (0.33) | PRMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17483961 | 0.72 | TERT (0.30) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623451-B1 | COMPOUND | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |