Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KDM4A | O75164 | 2/20 | 0.60 |
| ▸ | KDM4B | O94953 | 2/20 | 0.60 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.60 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.57 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376526 | 0.84 | ADORA3 (0.74) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL21376826 | 0.84 | ADORA3 (0.66) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL665571 | 0.83 | ADORA3 (0.78) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL21376819 | 0.82 | ADORA3 (0.69) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL21376517 | 0.82 | ADORA3 (0.80) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL16291393 | 0.79 | ADORA3 (0.83) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL21909810 | 0.79 | ADORA3 (0.65) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL31361475 | 0.78 | ADORA3 (0.81) | ADORA3MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL29978560 | 0.78 | ADORA3 (0.75) | ADORA3MAPTKDM4EMEN1KMT2A | |
| SCHEMBL664225 | 0.78 | ADORA3 (0.75) | ADORA3MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |