Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542553 | 0.80 | NPC1 (0.46) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL23997635 | 0.79 | KDM4E (0.42) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL8293208 | 0.79 | MEN1 (0.35) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL23652392 | 0.79 | MEN1 (0.37) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL16867407 | 0.77 | CYP1A2 (0.43) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10565368 | 0.77 | ADH1B (0.37) | ADH1BADH1CADH1AADH7PTGS2 | |
| SCHEMBL5545625 | 0.77 | KDM4E (0.50) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL21377524 | 0.75 | SRC (0.52) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL22854882 | 0.74 | HPGD (0.42) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL26568731 | 0.74 | P2RX7 (0.43) | ADH1BADH1CADH1AADH7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288945-B1 | IMIDAZOPYRAZINES AND PYRAZOLOPYRIMIDINES AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-18 | — | — | EP | disclosed |